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Amoxicillin Injection

Amoxicillin Injection
  • Amoxicillin Injection
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Product Details:

Type of MedicinesAllopathic
Dosage FormInjection
Medicine TypeAllopathic
Grade standardMedicine Grade

  • It is an Aminopenicillin, which is active against many strains of enterobacteriaceae. It is better absorbed from the GIT than ampicillin.
Composition : 250mg, 500mg,1gm
Indications : Acute cervical adenitis, acute otitismedia, acute sinusitis and acute bronchitis. Pneumonia in adult & children above 5 years, mild pneumonia in children aged from 2 months to 5 years, neonatal pneumonia together with gentamycin. Acute exacerbations of chronic bronchitis, chronic lung disease in children. Tooth abscess & suppurative odontogenic infections.
Contraindications :Known hypersensitivity to penicillins.
Safety Profile : Renal and hepatic diseases, infectious mononucleosis.
Adverse Effects :Hypersensitivity reactions, erythamatous, diarrhoea, neutropenia & thrombocytopenia.
Dosage :250-500 mg orally every 8 hours
15 mg/kg (Max 500mg) orally every 8 hrs
Purity :Not less than 99%
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Cefoperazone And Sulbactum Injection

Cefoperazone And Sulbactum Injection
  • Cefoperazone And Sulbactum Injection
  • Cefoperazone And Sulbactum Injection
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Product Details:

Medicine TypeAllopathic

  • Cefoperazone is third generation cephalosporin antibacterial component of Cefoperazone Sodium and Sulbactam Sodium, which acts against sensitive during the stage of active multiplication by inhibiting biosynthesis of cell wall mucopeptide. The combination has a broader spectrum of activity.
Composition : 0.5gm 0.5gm, 1gm 1gm
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Cefoperazone Injection

Cefoperazone Injection
  • Cefoperazone Injection
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Product Details:

Product Type Finished Product
Medicine Type Allopathic
UsageCommercial

  • The drug will be either injected into a large muscle (such as your buttock or hip) or added to an intravenous fluid that will drip through a needle or catheter placed in your vein for 30 minutes, two to four times a day. Cefoperazone eliminates bacteria that cause many kinds of infections, including lung, skin, bone, joint, stomach, blood, gynecological, and urinary tract infections. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information. Your health care provider (doctor, nurse or pharmacist) may measure the effectiveness and side effects of your treatment using laboratory tests and physical examinations. It is important to keep all appointments with your doctor and the laboratory. The length of treatment depends on how your infection and symptoms respond to the medication.

Precautions Before administering cefoperazone

  • Tell your doctor and pharmacist if you are allergic to cefoperazone or any other cephalosporin [Cefaclor (Ceclor), Cefadroxil (Duricef) or Cephalexin (Keflex)], Penicillins or any other drugs.
  • Tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially other antibiotics, probenecid (Benemid) and vitamins.
  • Tell your doctor if you have or have ever had kidney, liver, gallbladder or gastrointestinal disease (Especially colitis).
Composition : 250mg,500mg,1gm,2 gm
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Cefotaxime And Sulbactum Injection

Cefotaxime And Sulbactum Injection
  • Cefotaxime And Sulbactum Injection
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Product Details:

Product Type Finished Product
UsageCommercial
Medicine TypeAllopathic

  • It is an anti-infective combination of Cefotaxime and Sulbactam. Cefotaxime is a broad-spectrum semi-synthic third generation cephalosporin with potent bactericidal activity against a wide range of gram-positive and gram-negative bacteria. Sulbactam is beta lactamase inhibitor.
Composition : 500mg 250mg, 1gm 0.5gm
Indications : LRTI, GIT infections.
Dosage :Adult : Mild to moderate : 1g/0.5g to 2g/1g of cefotaxime/sulbactam every 8-12 hours.
Moderate to severe : 1g/0.5g to 2g/1g of cefotaxime/sulbactam every 6-8 hours.
Children : 100/50 to 150/75 mg of cefotaxime/sulbactam per kg b.w. per day in three divided doses.
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Central Nervous System Capsules

Central Nervous System Capsules
  • Central Nervous System Capsules
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Product Details:

Type of MedicinesAllopathic
Dosage Form (If Applicable)Capsules
Medicine TypeAllopathic
Product TypeFinished Product
Usage Commerical
Grade standardMedicine Grade

Doxepin75mg . 100mg
Duloxetine 20mg, 30mg, 40mg, 60mg
Duloxetine Mecobalamin 20mg, 30mg, 40mg, 60mg 500mg
Fluoxetine20mg, 40mg

lmipramine75mg


Pregabalin100mg
Pregabalin Mecobalamin75mg 750mcg
Venlafaxine75mg
Ziprasidone 20mg, 40mg, 80mg
Zonisamide 25mg, 50mg, 100mg
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Dactinomycin Injection

Dactinomycin Injection
  • Dactinomycin Injection
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Product Details:

Form of MedicineInjection
UsageCommercial

  • Category: Anti-neoplastic. Each vial contains: Dactinomycin USP 500 mcg. Good evidence exists that this drug bind strongly, but reversibly, to DNA, interfering with synthesis of RNA (prevention of RNA polymerase elongation) and, consequently, with protein synthesis.
Specification-pH range- 5.5 to 7.5
Dactinomycin is a clear, gold-colored liquid given into a vein (IV).
A compound composed of a two cyclic peptides attached to a phenoxazine that is derived from streptomyces parvullus. It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than initiation, termination, or release. As a result of impaired mRNA production, protein synthesis also declines after dactinomycin therapy.
Indication :For treatment of Wilms' tumor, childhood rhabdomyosarcoma, Ewing's sarcoma and metastatic, nonseminomatous testicular cancer as part of a combination chemotherapy and/or multi-modality treatment regimen.
Dosage :-Dose intensity per 2-week cycle for adults or children should not exceed 15 mcg/kg/day or 400-600 mcg/m²/day intravenously for five days.
Contra Indications:-Active infection with chiken pox or herpes zoster (a severe generalized form of disease may occure), infants less than12 months.
Precautions:-This drug is not recommended for use during pregnancy. Precaution is advised when using this drug in the elderly because they may be more sensitive to the effects of the drug, especially the effect on blood cell production (myelosuppression).
Drug interaction: Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
Adverse effects: Nausea, vomiting, malaise, fatigue, cheilitis, dysphagia, bone marrow depression gastric ulceration, hepatitis, hepatomegaly, abnormal liver function, alopecia, skin eruotion.
Storage:Powder for injection at room temperature (59 Degree to 86 DegreeF). Protect from light and humidity.
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Gynaecology Tablets

Gynaecology Tablets
  • Gynaecology Tablets
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Approx. Price: Rs 1 / Pack

Product Details:

Type Of MedicinesAllopathic
UsageCommerical
Grade standardMedicine Grade
Form Of MedicinesTablets
Medicine TypeAllopathic
Dosage FormTablets

We have gained immense expertise in delivering Gynaecology Tablets to our clients. The offered range of gynaecology tablets is available in different compositions and sizes to cater to the diverse requirements of esteemed clients. Along with this, the offered range of gynaecology tablets is suitably checked on number of characteristics to ensure its conformation with the benchmarks of quality.

Features:

  • Effective for treating infertility, infections and allied diseases
  • Safe
  • Effective
Asparagus Recemosus Multivitamins & Minerals-
Clomiphene Citrate25mg, 50mg, 100mg
Doxylamine Succinate Pyridoxine10mg 10mg
Doxylamine Succinate Pyridoxine Folic Acid10mg 10mg 5mg
Folic Acid5mg
Folic Acid Vitamin B12 Vit C5mg 15mcg 75mg
Ferrous Ascorbate Folic Acid ( Zinc Vit B12)350mg 1.5mg
Ferrous Ascorbate Folic Acid Adenosylcobalamin Vit B6 Zinc800mg 1.5mg 750mcg 3mg 16.8 mg
Folic Acid DHA Vit C Vit B125mg 250mg 75mg 15mcg
Isoxsuprine Hydrochloride40mg
Sodium Feredetate Adenosylcobalamine Folic Acid Vit B6 Zinc700mg 750mcg 5mg 3mg 16.8mg
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Iron Sorbitol Injection

Iron Sorbitol Injection
  • Iron Sorbitol Injection
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Product Details:

Product Type Finished Product
UsageCommercial

Composition : 75mg/1.5ml
Indications : Iron deficiency, anemia of those patients suffering from chronic haemodialysis.
Contraindications : Hypersensitivity,Iron overload
Safety Profile : Caution required in pregnancy, safety has not been established to administer in nursing mother, children and geriatric.
Adverse Effects : Hypotension, anaphylactoid reactions, musculoskeletal pain, diarrhoea, nausea vomiting, abdominal pain, pruritus, elevated liver enzymes, pain at injection site.
Drug Interaction: Conocomitant use with oral iron preparation.
Dosage :100mg (5ml) one to three times per week.
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Methyl Prednisolone Succinate Injection

Methyl Prednisolone Succinate Injection
  • Methyl Prednisolone Succinate Injection
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Product Details:

Product TypeFinished Product

  • Category: Antimalarial
Composition : 60mg
Artesunate: Artemisinin derivatives are the potent and rapidly acting blood schizonticides. These are cconcentrated in parasitized erythrocytes. Artesunate acts rapidly, stopping parasite development and preventing subsequent cytoadherence and resetting.Artesunate is well distributed and achieves high concentration in the intestines, liver and kidneys. Only a small amount of artesunate is excreted in the urine and in the stools.
Indications:Severe malaria including cerebral malaria and as a second line treatment in chloroquineresistant falciparum malaria.
Dosage : Adults : Parenteral:120gm on the first day followed by 60mg can be given on the first day itself 6 hours after the first dose.
Oral:100mg twice a day on the first day followed by 50mg twice daily for the next four days.
Children:1.2mg/kg x 5 days (maximum 60mg)
Contraindications: Not known
Special Precaution:Avoid in pregnant woman, especially in the first trimester.
Paediatrics:May be used if chloroquine resistant.
Pregnancy:Cpmtraomdocated on 1st trimester.
Lactation: Safety not established.
Side-Effects: Transient and reversible reticulocytopenia, drug fever, drug rash, bradycardia, transient first degree heart block and transient & revesible elevation of serum transaminases.
Lactation: Safety not established.
Drug Interactions: Antimalarial action potentiated by oxidant drugs. Additive effect seen with chloroquine. Antagonistic effect seen with pyrinethamine and sulfonamides.
Purity :Not less than 99%.
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Mitomycin Injection

Mitomycin Injection
  • Mitomycin Injection
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Product Details:

Product Type Finished Product
Form of MedicineInjection
UsageCommercial

  • It is an antibiotic isolated from streptomyces caespitosis, It selectively inhibits synthesis of DNA.
Composition : 2mg, 10mg & 40mg
Indications : Disseminated adenocarcinoma of stomach and pancreas.
Contraindications : Patients with previous idiosyncratic reaction to the drug, patient with thrombocytopenia, coagulation disorders, increase in bleeding tendency, pregnancy etc.
Adverse Effects : Fever, anorexia, nausea, vomiting, bone marrow, depression (within 8 weeks of onset of therapy) etc. Cellulitis at injection site, stomatitis, alopecia, renal impairment, pulmonary toxicity, haemolytic uraemia syndrome (micro angiopathic haemolytic anaemia, thrombocytopenia, irreversible, renal failure), congestive heart failure, headache, visual blurring, diarrhoea, pain etc.
Drug Interactions: Potentiates adriamycin induced cardiotoxicity. Synergestic with 5-flurouracil.
Dosage :20 mg/m² i.v. single dose via 1/2 catheter. Patient should be fully evaluated after each course and dose decrease if toxicity appears.
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Mitoxantrone Injection

Mitoxantrone Injection
  • Mitoxantrone Injection
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Product Details:

Form of MedicineInjection
UsageCommercial

  • It is a synthetic antineoplastic anthracenedione for intravenous use. Although its mechanism of action is not fully elucidated, it is DNA - reactive agent. It has a cytocidal effect on with proliferating and non proliferating cultured small cells suggesting lock of cell cycle specifically.
Composition : Each ml contains:
Mitoxantrone 2 mg
Indications : It is used in the treatment of metastatic breast cancer and of non-Hodgkin's lymphomas, alone or with other agents. It may also be given to treat adult acute myeloid leukemia. Mitoxantrone has also been used in patients with hormone-refractory prostate cancer, liver cancer, and ovarian cancer. In addition, mitoxantrone is used in the management of secondary progressive or relapsing multiple sclerosis, to reduce neurological disability or the frequency of relapses.

.
Contraindications : Mitoxantrone for injection is contraindicated in patients who have demonstrated prior hypersensitivity to it.
Adverse Effects : Serious adverse reactions including anaphylaxis and allergic reactions, neuropathy,pulmonary toxicities and hepatotoxicities can occur..
Dosage : In the treatment of breast cancer, prostate cancer, liver cancer, and lymphomas, a dose equivalent to mitoxantrone 14 mg/m2 is given initially and then repeated every 3 weeks. It is diluted to at least 50 ml in sodium
chloride 0.9% 5% and injected over at least 3 minutes into a freely-running intravenous infusion of
either. Subsequent doses may be adjusted according to the degree of Myelosuppression produced. Initial dosage
may need to be reduced to 12 mg/m2 in debilitated patients or those who have had previous Hemotherapy.
Precautions: Special Populations in Carcinogenesis, Mutagenesis, Impairment of Fertility, Hepatic Impairment, Pregnancy, Nursing Mothers, Pediatric Use, Geriatric Use, Multiple Sclerosis, Hormone-Refractory Prostate Cancer, Acute Nonlymphocytic Leukemia.
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Natural Progesterone Injection

Natural Progesterone Injection
  • Natural Progesterone Injection
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Product Details:

Product TypeFinished Product
UsageCommercial, Clinical, Hospital

  • Category:- Androgens
  • Each vial contains:-50mg,100mg & 200mg
  • Composition : 100mg/1ml,200mg/2ml
  • Indications: Premenstrual syndrome, maintenance of pregnancy in case of threatened or habitual abortion, sterlity due to luteal deficiency. In menopause to reduce the risk of endometrial hyperplasia and carcinoma in post menopausal woman receiving conjugated oestrogens. Puerperal depression.
  • Contraindications: Hypersensitivity, undiagnosed veginal bleeding, liver dysfunction , cerebral apoplexy, thrombophlebitis, thromboembolic disorders.
  • Safely profile: Migraine, asthma, esilepsy, renal dysfunction, driving or operating hazardous machinery should be avoided. Diabeted patients receiving oestrogen-prgesterone comination therapy should be monitored.
  • Adverse effects: Drowsiness, giddiness, weight gain/loss/rash, diarrhea/menstrual irregulations.
  • Dosage: Maintenance of pregnancy in cases of habitual or threatened abortion :200 to 400 mg per day in divided doses. For premenstrual syndrome :200-400 mg 1-2 times daily form the 12th to 14th day cycle until onset of menstruation
  • For puerperal depression : 400mg twice daily In devided doses. Supplementation of the luteal phase in case of sterility due to luteal deficiency :400 to 600 mg par day up to the 12th week of pregnancy.
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Netilmicin Injection

Netilmicin Injection
  • Netilmicin Injection
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Product Details:

Product TypeFinished Product
UsageHospital

Non steroidal anti-inflammatory drug with minimal gastric side effects has some selectivity for than . In addition to inhibition of prostaglandin synthesis, It also reduces generation of superoxide by neutrophils, inhibits PAF synthesis, inhibits TNE and inhibits proteinase activity in cartilage, thus preventing breakdown of osteo-arthritic human cartilage.
Composition :100mg/ml, 200mg/2ml, 300mg/3ml
Indications :Osteoarthritis, dysmenorrhoea, rheumatoid, arthritis, low back pain, dysmenorrhoea, dental pain, post operative pain, trauma.
Contraindications :GI bleed, peptic ulcer, hepatic dysfunction, pregnancy, lactation.
Safety Profile :Reduce dose in elderly, renal dysfunction, heart failure.
Adverse Effects :Epigastralgia, heart burn, nausea, loose motions, rash, pruritus, somnolence, dizziness.
Dosage :100mg twice a day
Children : 5 mg/kg/day in two or three divided dose.
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Octeriotide Injection

Octeriotide Injection
  • Octeriotide Injection
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Product Details:

Product Type Finished Product
UsageCommercial
Medicine TypeAllopathic

  • Category: Liquid Ampoules / Vials
  • Each vial contains:-Octreotide 50 mcg & 100 mcg per ml
  • Quality Specification:-Chromatographic Purity: NLT 99.5%.

  • It is a analogue of somatostatin and is a growth inhibitor. It suppress the secretion the secretion of GH It have antisecretory action by inhibiting secretion of gastrin & secretin.
Composition : 50mcg/ml, 100mcg/ml
Indication :Insulinomas, zollinger Ellison syndrome, acromegaly, vasoactive intestinal peptide tumours.
Contraindications :-Hypersensitivity.
Safety Profile :-In pregnancy or nursing mothers, it may be used if potential benefits overcome potential risks.
Adverse Effects :-Anorexia, GIT upsets, bloating, pain at inj. Site, pancreatitis.
Drug Interactions :Cimetidine, cyclosporine, cyanocobalamin, insulin.
Dosage :-Initially 0.05 to 0.1mg S.C. every 8-12 hrs max. 1.5 mg daily.
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Omeprazole Injection

Omeprazole Injection
  • Omeprazole Injection
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Product Details:

Type of MedicinesAllopathic
Product Type Finished Product
UsageCommercial
Dosage FormInjection
Medicine TypeAllopathic
Grade standardMedicine Grade

  • Omeprazole is gastric proton pump inhibitors. This prodrug is a substituted benzimidazole derivative which acts on the final step of gastiric acid production and therefore controls acid secretion in response to all varieties of stimuli, omerprazole has prolonged action in a dose of 20-40 mg once a day and reduces the 24 hours gastric acid output by almost 90%. It is highly effective in Zollinger-Ellison syndrome, recurrent duodenal ulcers & reflux oesophagitis. It also suppresses H-pylori. It should be taken before meals.
Composition : 20mg
Indications : Duodenal & gastric ulcers, NSAIDs induced ulcers, Zollinger-Ellison syndrome, reflux oesophagitis.
Contraindications : Hypersensitivity, pregnancy, lactation, children.
Safety Profile : Exclude the gastric malignancy, renal & hepatic dysfunction, epilepsy, avoid its use with alcohol.
Adverse Effects : Skin rashes, abdominal colic, diarrhoea, dry mouth, dizziness, headache, constipation & flatulence, increased risk of enteric
henytoin, cyclosporine & digoxin.
Dosage:Peptic ulcers - 20mg once daily for 4 weeks max up to 8 weeks.
Reflux oesophagitis-20-40mg once daily for 4-8 weeks.
Z.E.S. - 60mg once daily to start than 20-120mg daily in 2 divided dose.
Purity :Not less than 99%.
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Pain Killer Tablets

Pain Killer Tablets
  • Pain Killer Tablets
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Product Details:

Dosage FormTablet

  • Our organization is an eminent name, which is engaged in delivering Pain Killer Tablets to the respectable clients. The offered range of pain killer tablets is available in various compositions to append and respond to the diverse requirements of esteemed clients. In addition to this, the offered range of pain killer tablets is inspected on different characteristics to ensure its adherence with international quality norms and standards.

Features:

  • Precise compositions
  • Longer shelf life
Aceclofenac (Dispersible)100 mg
Aceclofenac (SR)200 mg
Aceclofenac Paracetamol100mg 500mg
Aceclofenac Paracetamol Serratiopeptidase100mg 500mg 15mg
Diclofenac Paracetamol Chlorzoxazone50mg 500mg 250mg
Etoricoxib90mg, 120mg
Lornoxicam Paracetamol8mg 500mg
Nimesulide100mg
Nimesulide Paracetamol100mg 500mg
Nimesulide Paracetamol Chlorzoxazone100mg 500mg 250mg
Nimesulide Paracetamol Serratiopeptidase100mg 500mg 15mg
Piroxicam20mg
Hydrochloride Paracetamol37.5mg, 50mg 325mg, 500mg
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Pamidronate Disodium Injection

Pamidronate Disodium Injection
  • Pamidronate Disodium Injection
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Product Details:

Product TypeFinished Product
UsageCommercial

  • How much to take?
Doctor will guide you how many tablets you need to take each day. This depends on your condition and whether you are taking other medicines.

For high blood pressure
: For most patients, the usual starting dose is one 50 mg tablet taken once a day. Some people may need a lower starting dose. The dose may need to be increased depending on your blood pressure.

For heart failure
: The usual starting dose is 12.5 mg taken once a day. Your doctor will increase this dose step by step until the amount that is right for you has been achieved. The usual long term dose is 50 mg, and should be taken once a day.
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Tobramycin Injection

Tobramycin Injection
  • Tobramycin Injection
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Product Details:

Dosage FormInjection

  • Category: Aminoglycosides
  • Each vial contains:- Tobramycin - 20mg, 60mg and 80mg
  • Quality Specification:-Chromatographic Purity - NLT 99.5%
Composition : 20mg/2 ml, 60mg/1.5ml, 80mg/2ml
TOBRAMYCIN: :-It is an aminoglycoside, highly soluble in water & stable for several week in solutions of various pH.
Indications :Treatment of external infection of the eye and its adnexa caused by susceptible strains of gram-positive, gram-negative & other probable bacteria. Safe & effective in children.
Dosage :-1-2 drops in the affected eye(s) every 4 hrs.
Adult :-Pneumonias, UTI, skin and skin structure infections: 500 mg 8 hourly.
Nosocomial Pneumonias, peritonitis, septicemia: 1gm every 8 hours.
Contra-Indications :-Hypersensitivity
Special Precautions :Not for injection into eye. If sensitivity reaction occurs, discontinue.
Paediatrics :-Safety is not established in patient with neutropenia or primary/secondary immuno-deficiency. Safety is not established in infants under 3 months of age.
Pregnancy :-Safety is not established.
Lactation :-Safety is not established.
Elderly :-Safe for elderly with normal renal functions.
Side-effects :-Localised ocular toxicity and hypersensitivity including itching and swelling and conjuctival erythema
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Verapamil Injection

Verapamil Injection
  • Verapamil Injection
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Product Details:

Product Type Finished Product
UsageCommercial
Medicine TypeAllopathic

  • It has potent antiarrhythmic activity more so in supraventricular arrhythmias because of its potent calcium channel blocking property. Same activity is responsible for its antianginal and antiischemic actions.
Composition : 5mg/ 2ml
Indications : PSVT, atrial flutter/fibrillation with tachyarrhythmias and pre mature beats. Angina pectoris, chronic coronary insufficiency, variant angina, hypertension.
Contraindications : Acute M.I., cardiovascular shock, severe AV block and sick sinus syndrome.
Safety Profile : Ability to do skilled job may be impaired, hepatic & renal impairment.
Adverse Effects : Constipation, nausea, dizziness, headache, flushing, faigue, ankle oedema, erythromelalia and paraesthesia.
Drug Interactions : Antihypertensives including beta blockers, neuromuscular blockers, digitalis and carbamazepine actions repotentiated. Use with quinidine may cause cardiac depression.
Dosage : Adults - 40-80 mg 2-3 times daily orally. i.v. dose 5mg slowly, repeat further 5mg if needed, children - upto 6 yrs. 40-80mg twice a day, 6-12 yrs - 40-120mg twice a day.
Purity :Not less than 99%.
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Vinblastine Injection

Vinblastine Injection
  • Vinblastine Injection
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Product Details:

TypeAllopathic
Medicine Type Allopathic

Composition : Each vial contains
Vinblastin Sulphate USP 1.0mg

Indications : Vinblastine sulfate (vinblastine sulfate injection) is indicated in the treatment of the following:

- Frequently Responsive Malignancies
- Generalized Hodgkin's disease
- Lymphocytic lymphoma (nodular and diffuse, poorly and well differentiated)
- Histiocytic lymphoma
- Mycosis fungoides (advanced stages)
- Advanced carcinoma of the testis
- Kaposi's sarcoma
- Letterer-Siwe disease
- Less Frequently Responsive Malignancies
- Choriocarcinoma resistant to other chemotherapeutic agents
- Carcinoma of the breast, unresponsive to appropriate endocrine surgery and hormonal therap
Contraindications : Pregnancy. Granulocytopenia, Bacterial infections.
Adverse Effects : Hair loss, leucopenia, neuritic pain, constipation, sensory loss, paresthesias, difficulty in walking (stepping gait), loss of deep tendon reflexes, muscle wasting, fever, hypersensitivity reaction, polyuria, urinary retention, hypertension, hypotension, cranial nerve palsy, headache, bone pains, jaw pain, parotid pain, myalgia, convulsions, syndrome of inappropriate secretion of ADH..
Dosage : Given I.V. at weekly intervals. Children : 2mg/m2 (if <10kg, start with 0.005 mg/kg/week) adult : 1.4mg/m2. Decrease the dose to 50%, if S. bilirubin is >3mg/dl. Not given to patients getting radiation therapy through ports that includes liver.
Precautions: Toxicity may be enhanced in the presence of hepatic insufficiency.
- Acute uric acid nephropathy,
- Acute shortness of breath
severe broncospasm have been reported following the administration of vinca alkaloids.
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Vincristine Injection

Vincristine Injection
  • Vincristine Injection
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Composition : 1mg/ml,2mg/2ml
Indications : Acute leukemia, lymphomas, Hodgkin's disease, non-Hodgkin lymphosarcoma, neuroblastoma, rhabdomyosarcoma, Wilm's tumour.
Contraindications :Pregnancy, lactation, demyelinating form of Charcot Marie tooth disease.
Safety Profile : The needle should be properly placed in the vein. If leakage occurs in surrounding tissues, considerable irritation will occur. Local injection of & moderate heat will minimize the discomfort. Used only by iv route. Considerable irritation can occur if extravasated into surrounding tissues.
Adverse Effects : Hair loss, leucopenia, neuritic pain, constipation, sensory loss, paraesthesia, difficulty in walking, loss of deep tendon reflexes, muscle wasting, fever, hypersensitivity reaction, weight loss, polyuria, urinary retention, hypertension, cranial nerve palsies, headache, bone pains, parotid pain, myalgia, convulsions, syndrome of inappropriate secretion of ADH.
Drug Interactions : If given with phenytoin, there is increased seizure activity. Acute bronchospasm with mitomycin-C.
Dosage : Given iv at weekly intervals.
Children : 2mg/m² (if <10kg, start with 0.05mg/kg/week).
Adult : 1.4 mg/m².
Decrease the dose to 50%, if S. bilirubin is >3mg/dl. Not given to patient getting radiation thereby through ports that include liver.
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