Category: Antibiotics and Antiinfectives
Each vial contains: Amoxycillin + Clavulanic Potassium…...1gm +200mg & 500mg + 100mg
Quality Specification: Chromatographic Purity: NLT 99.5%
Pack Size: vial
Amoxicillin + Clavulanic Acid
The two components of this combination product operate synergistically because clavulanic acid binds to lactase and there by competitively protects the amoxicillin against resistant lactamase producing strains. Both components are well absorbed after oral administration and are distributed into the lungs. They are largely excreted unchanged in the urine.
Infections caused by susceptible lactamase producing strains of E-Coli H. influenza klebsilla spp and streptococcus aureus. Acute otitis media, acule sinusitis, acute exacerbations of chronic bronchitis in adults.
Pneumonia amoxicillin 500mg+125mg of clavulanic acid every 8 hours.
Other Infections :
250mg amoxyicillin + 125mg Clavulanic t.i.d for 7 days.
|CEFTAZIDIME :||It is a broad spectrum, third generation parenteral cephalosporin effective against many Gram negative organisms.|
|Indication :||Serious infections of the respiratory tract, E.N.T, skin and soft tissue bone, and joints, biliary and G.I tract. U.T.I. Septicaemia, meningitis.infections in immunocompromised patients|
|Adults :||1-6 gm daily in divided doses every 8 or 12 hrs|
|Children (Over 1yr):||30-100 mg/kg body wt per day in 2-3 divided doses. Max 6 gm daily.|
|Contra-Indications :||Hypersensitivity to penicillins or Cephalosporins|
|Special Precautions :||Neonates and infants, renal of hepatic impairment, prolong use.|
|Paediatrics Safe :|
|Pregnancy & Lactation :||Use with caution|
|Elderly :||Decrease dose in case of renal impairment|
|Side effects :||G.I. disorders, pseudomembranous colitis, candidosis, eosinophilia, neutropenia, leucopenia, thrombocytopenia, rise in liver enzymes and blood urea. Pain at injection site.|
|Drug interactions :||Aminoglycosides, frusemide used concomitantly leads to nephrotoxicity, Chioramphenicol antagonizes ceftazidime|
Each vial contains: Acyclovir.. 250mg
Quality Specification: Chromatographic Purity: NLT 99.5%
Pack Size: vial
ACYCLOVIR: It is deoxiguanosine analog and requires a virus specific enzyme for conversion to the active metabolite that inhibits DNA synthesis and viral replication.
250mg & 500mg
Genital Herpes Simplex, Mucocutaneous H Simplex Encephalitis, H Simplex Keratitis, Herpes Zoster, Chicken Pox etc.
Adults: Herpes Simplex: 200 mg 5 times daily at 4 hrs interval for 5 days Herpes Zoster: 800 mg 5 times daily 4 hrs interval for 7 days Prophylaxis in Suppression: 200 mg 4 times daily
(Abpve 2 yrs) Dose same as adult.
(Below 2 yrs) Herpes Simplex: 100 mg 5 times at 4 hrs interval Prophylaxis: 100 mg 4 times daily at 6 hrs interval.
Hypersensitivity, glaucoma, psychiatric diseases, depression etc.
Special Precautions :
Renal impairment necessitates dose reduction. Maintain adequate hydration
Reduced dose necessary. Not recommended in age below 2 years.
Contraindicated orally and parentally.
May reduce lactation
|Indications :-||Respiratory tract, (Staphylococci and Pneumococci) skin and soft tissues, dental, nasopharyngal infections.|
|Dosage :||Mild to moderately severs infection 150 to 300 mg 6 hourly. Severe infections :- 300 to 450 mg 6 hourly.|
|Contra-Indication :-||Hyersensitivty to clindamycin or Lincomycin in newborns and infants.|
|Special Precautions :-||Use in atopic individuals, periodic liver function test and blood count, hepatic and renal impairment.|
|Paediatrics :-||Contra-indicated in infants|
|Drug Interactions :-||Erythromycin acts as an antagonist, pancuronium induced neuromuscular blockade, reduced absorption rate in presence of kaolin- pectin, synergistic effect with gentamycin.|
|Composition :||250mg, 500mg,1gm|
|Indications :||Acute cervical adenitis, acute otitismedia, acute sinusitis and acute bronchitis. Pneumonia in adult & children above 5 years, mild pneumonia in children aged from 2 months to 5 years, neonatal pneumonia together with gentamycin. Acute exacerbations of chronic bronchitis, chronic lung disease in children. Tooth abscess & suppurative odontogenic infections. Acute gastritis and peptic ulcer disease. Osteomylitis lyme disease.|
|Contraindications :||Known hypersensitivity to penicillins.|
|Safety Profile :||Renal and hepatic diseases, infectious mononucleosis.|
|Adverse Effects :||Hypersensitivity reactions, erythamatous, diarrhoea, neutropenia & thrombocytopenia.|
|Dosage :||250-500 mg orally every 8 hours|
15 mg/kg (Max 500mg) orally every 8 hours
|Composition :||100mg, 200 mg|
Your doctor has prescribed piperacillin and tazobactam, an antibiotic, to help treat your infection. The drug will be added to an intravenous fluid that will drip through a needle or catheter placed in your vein for 30 minutes, three or four times a day.
The combination of piperacillin and tazobactam eliminates bacteria that cause many kinds of infections, including pneumonia and skin, stomach, and gynecological infections. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
Your health care provider (doctor, nurse, or pharmacist) may measure the effectiveness and side effects of your treatment using laboratory tests and physical examinations. It is important to keep all appointments with your doctor and the laboratory. The length of treatment depends on how your infection and symptoms respond to the medication.
|Composition :||100mg/2ml, 250 mg/2ml & 500mg/2ml|
|Amikacin:||It is semisynthetic aminoglycoside virtually identical to its parent compound kanamycin. Amikacin is effective against a variety of aerobic gram-negative bacilli including those that are resistant to gentamicin and other Aminoglycosides (Escherichia Coli, Pseudomonas Aeruginosa, Indole positive and negative Proteus species Klebsiella, Enterobacter, Serratia, Acinetobacter, Citobacter Freundii and providencia stuarti). It is effective against both penicillinase and non-penicillinase producing Staphylococcus Aureus. Amikacin shows excellent activity against Mycobacterium Tuberculosis and Atypical Mycobacteria.|
|Indications :||Bacteraemias, septicaemias, respiratory tract, bone and joints, CNS (including meningitis), soft tissue, intra-abdominal infections (including peritonitis), burns and post-operative infections.|
|Product Type||Finished Product|
|Indications :||Orally used for prevention of graft rejection after kidney, liver, heart, lung, pancreas. By IV infusion used in bone marrow transplant.|
Warnings - Cyclosporine when used in higher doses can cause hepatotoxicity and nephrotoxicity. Vaccinationus are less effective with its use.
|Safety Profile :||Elderly, thyrotoxicosis, renal or hepatic diseases and acute myocardial infection.|
Nausea, Headache, Indigestion, Vomiting, Abdominal pain, Diarrhea
|Composition :||20mg/2ml, 40mg/1ml, 80mg/2ml, 400mg/10ml,1200mg/30ml|
|Gentamicin:||Potent antibiotic having a broader spectrum of action against a wide variety of bacterial infections.|
|Indications :||Valuable in critically ill patients, with impaired host defence, burns, urinary tract infections, lung abscesses, osteomyelitis, middle ear infection, septicaemia, meningitis caused by gram negative bacilli.|
|Dosage :||3-5 mg/kg body wt IM or IV daily in 3 divided doses for 7 to 10 days, 25-50 mg/kg/day|
|Contra-indications :-||Uraemia, severe renal function impairment; pregnancy, neonatals (except in life threatening situations)|
|Special Precautions:||Dose of gentamicin must be precisely calculated according to body wt and level of renal function.|
|Paediatrics :||Reduced dose necessary.|
|Elderty:||Reduced dose may be necessary due to adverse effects.|
|Side Effects:||Irreversible ototoxicity, nephrotoxicity headache, rashes, thrombocytopenia and joint pain.|
|Drug Interactions :||Increased incidence of toxicity when combined with ethacrynic acid, risk of loss of hearing/kidney failure. Cephalosporins, hydrocortisone & indomethacin potentiate nephrotoxicity, neuro-muscular blocking agents.|
|Safety Profile :||Fluid and electrolyte imbalance, cardiomyopathy, aortic diseases, aortic diseases, pregnancy and lactation.|
|Adverse Effects :||Cardiac arrhythmias, nausea, hepatotoxicity, hypotension, G.I.Disturbances.|
|Drug Interactions:||Enhanced hypotensive response when used with disopyramide.|
|Dosage:||Loading dose 0.75 mg/kg/i.v.|
|Milrinone :||I. V. administration.|
|Indications :||Short term management of CCF in patient unresponsive to digitalis diuretics or vasodilators|
|Adverse Effects :||Ventricular arrhythmias, hypokalemia, tremors.|
|Dosage :||Initially start with 0.5 mg/kg. Followed by intravenous infusion at a rate of 375-750 nanograms/kg/min.|
|25mg/2.5ml & 50mg/5ml|
|Chemical:||A benzyl isoquinolonium ester. It is a short-acting relaxant, which is rapidly broken down by the body. This makes atracurium very predictable, as it wears off rapidly compared with the longer-acting relaxants.|
|Cardiovascular effects :||Although atracurium produces few direct circulatory effects, the absence of vagal blocking activity makes the patient vulnerable to bradycardias during anaesthesia. Histamine release may occur with doses of atracurium greater than 0.6 mg/kg. Histamine may also be released if atracurium precipitates in the syringe or vein. This may occur if atracurium is injected immediately after thiopentone.|
|Respiratory effects:||In standard doses, atracurium rarely causes problems with bronchospasm. Bronchospasm can occasionally occur secondary to histamine release. Placental transfer is insignificant and the drug is widely used in obstetrics.|